Safety, target engagement, and biomarker effects of bosutinib in dementia with Lewy bodies – May 2022
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CSF MicroRNAs Reveal Impairment of Angiogenesis and Autophagy in Parkinson Disease – December 2021
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Long-Term Safety and Clinical Effects of Nilotinib in Parkinson’s Disease – November 2020
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Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer’s Disease – May 2020
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Towards a biomarker system that supports disease modifying therapies in Parkinson’s disease – March 2020
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Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease – December 2019
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Multikinase Abl/DDR/Src Inhibition Produces Optimal Efects for Tyrosine Kinase Inhibition in Neurodegeneration – June 2019
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Pharmacokinetics and pharmacodynamics of a single dose Nilotinib in individuals with Parkinson’s disease – March 2019
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Tau clearance improves astrocytic function and brain glutamate-glutamine cycle – August 2018
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Activating Autophagy as a Therapeutic Strategy for Parkinson’s Disease – January 2018
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Discoidin domain receptor inhibition reduces neuropathology and attenuates inflammation in neurodegeneration models – October 2017
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Could cancer drugs be repurposed for use in Parkinson’s and Alzheimer’s? – December 2016
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Tyrosine kinase inhibition reverses TDP-43 effects on synaptic protein expression, astrocytic function and amino acid dis-homeostasis. – November 2016
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Nilotinib Effects in Parkinson’s Disease and Dementia with Lewy Bodies – July 2016
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Two sides of the same coin: tyrosine kinase inhibition in cancer and neurodegeneration – November 2015
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Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer’s disease models – July 2015
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Tau deletion impairs intracellular β-amyloid-42 clearance and leads to more extracellular plaque deposition in gene transfer models – November 2014
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Tyrosine Kinase Inhibition Regulates Early Systemic Immune Changes and Modulates the Neuroimmune Response in αSynucleinopathy – September 2014
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Parkin-mediated reduction of nuclear and soluble TDP-43 reverses behavioral decline in symptomatic mice – September 2014
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Nilotinib-induced autophagic changes increase endogenous parkin level and ubiquitination, leading to amyloid clearance – December 2013
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Ubiquitination Increases Parkin Activity to Promote Autophagic a-Synuclein Clearance – December 2013
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Tyrosine kinase inhibition facilitates autophagic SNCA/α-synuclein clearance – August 2013
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Tyrosine kinase inhibition increases functional parkin‐Beclin‐1 interaction and enhances amyloid clearance and cognitive performance – August 2013
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Nilotinib reverses loss of dopamine neurons and improvesmotor behavior via autophagic degradation of a-synuclein in Parkinson’s disease models – May 2013
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Decreased parkin solubility is associated with impairment of autophagy in the nigrostriatum of sporadic Parkinson’s disease – December 2012
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